Tuesday, June 26, 2012
The prefilled syringe
Intravenous Infusion
Intravenous Infusion
IV infusion is a direct method by which the drug is administered systematically in to the body.It is given either as a bolus or infused slowly drip by drip.Compared with other routes of administration, the intravenous route is the fastest way to deliver fluids and medications throughout the body. Some medications, as well as blood transfusions and lethal injections, can only be given intravenously.
Advantage
Precise control of plasma drug concentration
The rate can be controlled
For large volume of parenteral dose, it is wise to use infusion to remain the blood
volume , pH, buffer system unchanged
Some drugs can’t given in large volume (like heparine) because that may cause heart
collapse in that case Infusion is ideal
Some drugs can’t take orally so infusion is used
With a narrow therapeutic window contained drugs given as infusion
Less toxicity
Bioavailability is high
Dose accuracy
Disadvantage
Infection may arise at the infusion site
Supervisor needed
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