Intravenous Infusion

Intravenous Infusion IV infusion is a direct method by which the drug is administered systematically in to the body.It is given either as a bolus or infused slowly drip by drip.Compared with other routes of administration, the intravenous route is the fastest way to deliver fluids and medications throughout the body. Some medications, as well as blood transfusions and lethal injections, can only be given intravenously. Advantage Precise control of plasma drug concentration The rate can be controlled For large volume of parenteral dose, it is wise to use infusion to remain the blood volume , pH, buffer system unchanged Some drugs can’t given in large volume (like heparine) because that may cause heart collapse in that case Infusion is ideal Some drugs can’t take orally so infusion is used With a narrow therapeutic window contained drugs given as infusion Less toxicity Bioavailability is high Dose accuracy Disadvantage Infection may arise at the infusion site Supervisor needed